After configuring our ShareFile to integrate our AD accounts using AD FS 2.0 and SAML for login, we found several user could not log in with Chrome or Firefox. They would go to the SAML login URL and then enter their correct AD credentials. The login would then fail. Using IE with the same credentials was successful. After investigation, the issue was linked to AD FS 2.0 and Chrome/Firefox, not ShareFile.
The Solution below was found at http://exitcodezero.wordpress.com/2013/05/30/adfs-authentication-issues-with-chrome-and-firefox/
To correct the issues, disable Extended Protection in IIS on your ADFS server